Variety glandulissima grows in the Ridge and Valley region of central and eastern Tennessee and adjacent Alabama, Kentucky, Mississippi, and Virginia. It is introduced and established in northern Arkansas, southern Missouri, northeastern North Carolina; occurrences in southern Michigan and northern New Jersey probably were emphemeral and did not persist.
Variety glandulissima often is taller than 100 cm and obviously stipitate-glandular. The variety appears to have evolved within historic times in Tennessee, or only recently to have evolved the traits necessary to make it a successful roadside weed. J. C. Semple (1983) discussed its range expansion over the last 100 years; it continues to expand its range in the eastern United States.